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Could pharmacogenetic data explain part of the interindividual sensitivity to methadone-induced respiratory depression?
In this issue of Critical Care, Megarbane and colleagues present a case report of methadone-induced respiratory depression and conduct a toxicokinetic/toxicodynamic evaluation. An opioid-dependent patient receiving methadone maintenance treatment (daily dose 70 mg) was found unconscious after ingest...
Autores principales: | Crettol, Séverine, Monnat, Martine, Eap, Chin B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151888/ https://www.ncbi.nlm.nih.gov/pubmed/17338832 http://dx.doi.org/10.1186/cc5699 |
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