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Soluble Adenylyl Cyclase Is Localized to Cilia and Contributes to Ciliary Beat Frequency Regulation via Production of cAMP
Ciliated airway epithelial cells are subject to sustained changes in intracellular CO(2)/HCO(3) (−) during exacerbations of airway diseases, but the role of CO(2)/HCO(3) (−)-sensitive soluble adenylyl cyclase (sAC) in ciliary beat regulation is unknown. We now show not only sAC expression in human a...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2154360/ https://www.ncbi.nlm.nih.gov/pubmed/17591988 http://dx.doi.org/10.1085/jgp.200709784 |