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A Direct Demonstration of Closed-State Inactivation of K(+) Channels at Low pH

Lowering external pH reduces peak current and enhances current decay in Kv and Shaker-IR channels. Using voltage-clamp fluorimetry we directly determined the fate of Shaker-IR channels at low pH by measuring fluorescence emission from tetramethylrhodamine-5-maleimide attached to substituted cysteine...

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Detalles Bibliográficos
Autores principales:	Claydon, Thomas W., Vaid, Moni, Rezazadeh, Saman, Kwan, Daniel C.H., Kehl, Steven J., Fedida, David
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2154379/ https://www.ncbi.nlm.nih.gov/pubmed/17470663 http://dx.doi.org/10.1085/jgp.200709774

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