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Convergent Use of RhoGAP Toxins by Eukaryotic Parasites and Bacterial Pathogens
Inactivation of host Rho GTPases is a widespread strategy employed by bacterial pathogens to manipulate mammalian cellular functions and avoid immune defenses. Some bacterial toxins mimic eukaryotic Rho GTPase-activating proteins (GAPs) to inactivate mammalian GTPases, probably as a result of evolut...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156102/ https://www.ncbi.nlm.nih.gov/pubmed/18166080 http://dx.doi.org/10.1371/journal.ppat.0030203 |