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Mcm2, but Not Rpa, Is a Component of the Mammalian Early G1-Phase Prereplication Complex
Previous experiments in Xenopus egg extracts identified what appeared to be two independently assembled prereplication complexes (pre-RCs) for DNA replication: the stepwise assembly of ORC, Cdc6, and Mcm onto chromatin, and the FFA-1–mediated recruitment of RPA into foci on chromatin. We have invest...
Autores principales: | Dimitrova, Daniela S., Todorov, Ivan T., Melendy, Thomas, Gilbert, David M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156148/ https://www.ncbi.nlm.nih.gov/pubmed/10459007 |
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