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The Spinal Muscular Atrophy Disease Gene Product, Smn: A Link between Snrnp Biogenesis and the Cajal (Coiled) Body
The spliceosomal snRNAs U1, U2, U4, and U5 are synthesized in the nucleus, exported to the cytoplasm to assemble with Sm proteins, and reimported to the nucleus as ribonucleoprotein particles. Recently, two novel proteins involved in biogenesis of small nuclear ribonucleoproteins (snRNPs) were ident...
Autores principales: | Carvalho, Teresa, Almeida, Fátima, Calapez, Alexandre, Lafarga, Miguel, Berciano, Maria T., Carmo-Fonseca, Maria |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2156166/ https://www.ncbi.nlm.nih.gov/pubmed/10562276 |
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