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Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2

The muscle-specific RING finger proteins MuRF1 and MuRF2 have been proposed to regulate protein degradation and gene expression in muscle tissues. We have tested the in vivo roles of MuRF1 and MuRF2 for muscle metabolism by using knockout (KO) mouse models. Single MuRF1 and MuRF2 KO mice are healthy...

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Detalles Bibliográficos
Autores principales: Witt, Christian C, Witt, Stephanie H, Lerche, Stefanie, Labeit, Dietmar, Back, Walter, Labeit, Siegfried
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168395/
https://www.ncbi.nlm.nih.gov/pubmed/18157088
http://dx.doi.org/10.1038/sj.emboj.7601952