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The Drosophila Cytosine-5 Methyltransferase Dnmt2 Is Associated with the Nuclear Matrix and Can Access DNA during Mitosis

Cytosine-5 methyltransferases of the Dnmt2 family are highly conserved in evolution and their biological function is being studied in several organisms. Although all structural DNA methyltransferase motifs are present in Dnmt2, these enzymes show a strong tRNA methyltransferase activity. In line wit...

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Detalles Bibliográficos
Autores principales: Schaefer, Matthias, Steringer, Julia P., Lyko, Frank
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169302/
https://www.ncbi.nlm.nih.gov/pubmed/18183295
http://dx.doi.org/10.1371/journal.pone.0001414