Interaction among Gsk-3, Gbp, Axin, and APC in Xenopus Axis Specification

Glycogen synthase kinase 3 (GSK-3) is a constitutively active kinase that negatively regulates its substrates, one of which is β-catenin, a downstream effector of the Wnt signaling pathway that is required for dorsal–ventral axis specification in the Xenopus embryo. GSK-3 activity is regulated throu...

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Detalles Bibliográficos
Autores principales: Farr, Gist H., Ferkey, Denise M., Yost, Cynthia, Pierce, Sarah B., Weaver, Carole, Kimelman, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169372/
https://www.ncbi.nlm.nih.gov/pubmed/10684251

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