Identification of Ubiquilin, a Novel Presenilin Interactor That Increases Presenilin Protein Accumulation

Mutations in the highly homologous presenilin genes encoding presenilin-1 and presenilin-2 (PS1 and PS2) are linked to early-onset Alzheimer's disease (AD). However, apart from a role in early development, neither the normal function of the presenilins nor the mechanisms by which mutant protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Mah, Alex L., Perry, George, Smith, Mark A., Monteiro, Mervyn J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169435/
https://www.ncbi.nlm.nih.gov/pubmed/11076969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169435/
https://www.ncbi.nlm.nih.gov/pubmed/11076969

Ejemplares similares