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Identification of a Molecular Target of Psychosine and Its Role in Globoid Cell Formation

Globoid cell leukodystrophy (GLD) is characterized histopathologically by apoptosis of oligodendrocytes, progressive demyelination, and the existence of large, multinuclear (globoid) cells derived from perivascular microglia. The glycosphingolipid, psychosine (d-galactosyl-β-1,1′ sphingosine), accum...

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Detalles Bibliográficos
Autores principales:	Im, Dong-Soon, Heise, Christopher E., Nguyen, Tuan, O'Dowd, Brian F., Lynch, Kevin R.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2001
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169470/ https://www.ncbi.nlm.nih.gov/pubmed/11309421

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