A Nuclear Action of the Eukaryotic Cochaperone Rap46 in Downregulation of Glucocorticoid Receptor Activity

RAP46 is a eukaryotic cochaperone that associates with several proteins, including the heat shock protein hsp70/hsc70 and the glucocorticoid receptor (GR). Here we show a downregulation of GR-mediated transactivation by RAP46 via a mechanism independent of a cytoplasmic action of this cochaperone. W...

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Detalles Bibliográficos
Autores principales: Schneikert, Jean, Hübner, Susanne, Martin, Elke, Cato, Andrew C.B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169481/
https://www.ncbi.nlm.nih.gov/pubmed/10477749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169481/
https://www.ncbi.nlm.nih.gov/pubmed/10477749

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