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Trypanosoma brucei Polo-like kinase is essential for basal body duplication, kDNA segregation and cytokinesis
Polo-like kinases (PLKs) are conserved eukaryotic cell cycle regulators, which play multiple roles, particularly during mitosis. The function of Trypanosoma brucei PLK was investigated in procyclic and bloodstream-form parasites. In procyclic trypanosomes, RNA interference (RNAi) of PLK, or overexpr...
Autores principales: | Hammarton, Tansy C, Kramer, Susanne, Tetley, Laurence, Boshart, Michael, Mottram, Jeremy C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169650/ https://www.ncbi.nlm.nih.gov/pubmed/17662039 http://dx.doi.org/10.1111/j.1365-2958.2007.05866.x |
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