Cargando…

Alterations in local chromatin environment are involved in silencing and activation of subtelomeric var genes in Plasmodium falciparum

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), encoded by the var gene family, undergoes antigenic variation and plays an important role in chronic infection and severe malaria. Only a single var gene is transcribed per parasite, and epigenetic control mechanisms are fundamental in t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Voss, Till S, Tonkin, Christopher J, Marty, Allison J, Thompson, Jennifer K, Healer, Julie, Crabb, Brendan S, Cowman, Alan F
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2007
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169929/ https://www.ncbi.nlm.nih.gov/pubmed/17725559 http://dx.doi.org/10.1111/j.1365-2958.2007.05899.x

Ejemplares similares

Plasmodium falciparum virulence determinants unveiled
por: Crabb, Brendan S, et al.
Publicado: (2002)

Analysis of subtelomeric virulence gene families in Plasmodium falciparum by comparative transcriptional profiling
por: Witmer, Kathrin, et al.
Publicado: (2012)

Ultra-Sensitive Detection of Plasmodium falciparum by Amplification of Multi-Copy Subtelomeric Targets
por: Hofmann, Natalie, et al.
Publicado: (2015)

Transcriptome analysis of antigenic variation in Plasmodium falciparum - var silencing is not dependent on antisense RNA
por: Ralph, Stuart A, et al.
Publicado: (2005)

Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA
por: Chen, Lin, et al.
Publicado: (2017)

Environment-responsive transcription factors bind subtelomeric elements and regulate gene silencing
por: Smith, Jennifer J, et al.
Publicado: (2011)

A var Gene Upstream Element Controls Protein Synthesis at the Level of Translation Initiation in Plasmodium falciparum
por: Brancucci, Nicolas M. B., et al.
Publicado: (2014)

The role of N-terminus of Plasmodium falciparum ORC1 in telomeric localization and var gene silencing
por: Deshmukh, Abhijit S., et al.
Publicado: (2012)

Genome-wide nucleosome mapping of Plasmodium falciparum reveals histone-rich coding and histone-poor intergenic regions and chromatin remodeling of core and subtelomeric genes
por: Westenberger, Scott J, et al.
Publicado: (2009)

Subtelomeric Chromatin in the Fission Yeast S. pombe
por: Yadav, Rajesh K., et al.
Publicado: (2021)

Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres
por: Otto, Thomas D., et al.
Publicado: (2018)

Differential, Positional-Dependent Transcriptional Response of Antigenic Variation (var) Genes to Biological Stress in Plasmodium falciparum
por: Rosenberg, Elli, et al.
Publicado: (2009)

A highly conserved segmental duplication in the subtelomeres of Plasmodium falciparum chromosomes varies in copy number
por: Mok, Bobo W, et al.
Publicado: (2008)

Identification of a cis-acting DNA–protein interaction implicated in singular var gene choice in Plasmodium falciparum
por: Brancucci, Nicolas M B, et al.
Publicado: (2012)

Protein Kinase A Is Essential for Invasion of Plasmodium falciparum into Human Erythrocytes
por: Wilde, Mary-Louise, et al.
Publicado: (2019)

PfSWIB, a potential chromatin regulator for var gene regulation and parasite development in Plasmodium falciparum
por: Wang, Wei-Feng, et al.
Publicado: (2020)

Silencing subtelomeric VSGs by Trypanosoma brucei RAP1 at the insect stage involves chromatin structure changes
por: Pandya, Unnati M., et al.
Publicado: (2013)

Silencing subtelomeric VSGs by Trypanosoma brucei RAP1 at the insect stage involves chromatin structure changes
por: Pandya, Unnati M, et al.
Publicado: (2013)

Sir2 Paralogues Cooperate to Regulate Virulence Genes and Antigenic Variation in Plasmodium falciparum
por: Tonkin, Christopher J, et al.
Publicado: (2009)

Plasmodium falciparum Plasmodium helical interspersed subtelomeric proteins contribute to cytoadherence and anchor P. falciparum erythrocyte membrane protein 1 to the host cell cytoskeleton
por: Oberli, Alexander, et al.
Publicado: (2016)

Systematic profiling of subtelomeric silencing factors in budding yeast
por: Juárez-Reyes, Alejandro, et al.
Publicado: (2023)

PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum
por: Scally, Stephen W., et al.
Publicado: (2022)

A computational model of gene expression reveals early transcriptional events at the subtelomeric regions of the malaria parasite, Plasmodium falciparum
por: Scholz, Matthias, et al.
Publicado: (2008)

A Genome-wide Chromatin-associated Nuclear Peroxiredoxin from the Malaria Parasite Plasmodium falciparum
por: Richard, Dave, et al.
Publicado: (2011)

Development of fluorescent Plasmodium falciparum for in vitro growth inhibition assays
por: Wilson, Danny W, et al.
Publicado: (2010)

Conditional expression of apical membrane antigen 1 in Plasmodium falciparum shows it is required for erythrocyte invasion by merozoites
por: Yap, Alan, et al.
Publicado: (2014)

Architecture, Chromatin and Gene Organization of Toxoplasma gondii Subtelomeres
por: Contreras, Susana M., et al.
Publicado: (2022)

Nanobodies against Pfs230 block Plasmodium falciparum transmission
por: Dietrich, Melanie H., et al.
Publicado: (2022)

Plasmodium falciparum Adhesins Play an Essential Role in Signalling and Activation of Invasion into Human Erythrocytes
por: Tham, Wai-Hong, et al.
Publicado: (2015)

Vaccination with Conserved Regions of Erythrocyte-Binding Antigens Induces Neutralizing Antibodies against Multiple Strains of Plasmodium falciparum
por: Healer, Julie, et al.
Publicado: (2013)

Population Genomics of the Immune Evasion (var) Genes of Plasmodium falciparum
por: Barry, Alyssa E, et al.
Publicado: (2007)

Diversity of the var gene family of Indonesian Plasmodium falciparum isolates
por: Sulistyaningsih, Erma, et al.
Publicado: (2013)

Association of antibodies to Plasmodium falciparum reticulocyte binding protein homolog 5 with protection from clinical malaria
por: Chiu, Chris Y. H., et al.
Publicado: (2014)

CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparum
por: Bryant, Jessica M., et al.
Publicado: (2017)

Unravelling var complexity: Relationship between DBLα types and var genes in Plasmodium falciparum
por: Tan, Mun Hua, et al.
Publicado: (2022)

Roles of Specialized Chromatin and DNA Structures at Subtelomeres in Schizosaccharomyces pombe
por: Kanoh, Junko
Publicado: (2023)

Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes
por: Chen, Lin, et al.
Publicado: (2014)

Highly condensed chromatins are formed adjacent to subtelomeric and decondensed silent chromatin in fission yeast
por: Matsuda, Atsushi, et al.
Publicado: (2015)

Biochemical and Functional Analysis of Two Plasmodium falciparum Blood-Stage 6-Cys Proteins: P12 and P41
por: Taechalertpaisarn, Tana, et al.
Publicado: (2012)

Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes
por: Maier, Alexander G., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_8k62h3geomv8sk7isjv8pr0uap