Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report

We describe a patient with previously undiagnosed hypothyroidism who developed rhabdomyolysis while taking a statin. He had no other precipitating factors. The statin was stopped, intravenous fluids were started immediately and L-thyroxin was given after confirming the diagnosis of hypothyroidism. H...

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Detalles Bibliográficos
Autores principales: Yeter, Ekrem, Keles, Telat, Durmaz, Tahir, Bozkurt, Engin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2170445/
https://www.ncbi.nlm.nih.gov/pubmed/17996111
http://dx.doi.org/10.1186/1752-1947-1-130
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author Yeter, Ekrem
Keles, Telat
Durmaz, Tahir
Bozkurt, Engin
author_facet Yeter, Ekrem
Keles, Telat
Durmaz, Tahir
Bozkurt, Engin
author_sort Yeter, Ekrem
collection PubMed
description We describe a patient with previously undiagnosed hypothyroidism who developed rhabdomyolysis while taking a statin. He had no other precipitating factors. The statin was stopped, intravenous fluids were started immediately and L-thyroxin was given after confirming the diagnosis of hypothyroidism. His symptoms improved over a few days. Because rhabdomyolysis is a rare but potentially life threatening disorder when complicated by acute tubular necrosis and renal failure, physicians must pay special attention when starting statins in patients with hyperlipidemia.
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spelling pubmed-21704452008-01-01 Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report Yeter, Ekrem Keles, Telat Durmaz, Tahir Bozkurt, Engin J Med Case Reports Case Report We describe a patient with previously undiagnosed hypothyroidism who developed rhabdomyolysis while taking a statin. He had no other precipitating factors. The statin was stopped, intravenous fluids were started immediately and L-thyroxin was given after confirming the diagnosis of hypothyroidism. His symptoms improved over a few days. Because rhabdomyolysis is a rare but potentially life threatening disorder when complicated by acute tubular necrosis and renal failure, physicians must pay special attention when starting statins in patients with hyperlipidemia. BioMed Central 2007-11-10 /pmc/articles/PMC2170445/ /pubmed/17996111 http://dx.doi.org/10.1186/1752-1947-1-130 Text en Copyright © 2007 Yeter et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yeter, Ekrem
Keles, Telat
Durmaz, Tahir
Bozkurt, Engin
Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report
title Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report
title_full Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report
title_fullStr Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report
title_full_unstemmed Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report
title_short Rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report
title_sort rhabdomyolysis due to the additive effect of statin therapy and hypothyroidism: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2170445/
https://www.ncbi.nlm.nih.gov/pubmed/17996111
http://dx.doi.org/10.1186/1752-1947-1-130
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AT durmaztahir rhabdomyolysisduetotheadditiveeffectofstatintherapyandhypothyroidismacasereport
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