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Geranylgeranylacetone Ameliorates Inflammatory Response to Lipopolysaccharide (LPS) in Murine Macrophages: Inhibition of LPS Binding to The Cell Surface

We investigated whether pretreatment with geranylgeranylacetone (GGA), a potent heat shock protein (HSP) inducer, could inhibit proinflammatory cytokine liberation and nitric oxide (NO) production in lipopolysaccharide (LPS)-treated murine macrophages. The levels of NO and tumor necrosis factor-α (T...

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Detalles Bibliográficos
Autores principales:	Mochida, Shinsuke, Matsura, Tatsuya, Yamashita, Atsushi, Horie, Shunsuke, Ohata, Shuzo, Kusumoto, Chiaki, Nishida, Tadashi, Minami, Yukari, Inagaki, Yoshimi, Ishibe, Yuichi, Nakada, Junya, Ohta, Yoshiji, Yamada, Kazuo
Formato:	Texto
Lenguaje:	English
Publicado:	the Society for Free Radical Research Japan 2007
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2170953/ https://www.ncbi.nlm.nih.gov/pubmed/18193105 http://dx.doi.org/10.3164/jcbn.2007016

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