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Analysis of the Xenopus Werner syndrome protein in DNA double-strand break repair

Werner syndrome is associated with premature aging and increased risk of cancer. Werner syndrome protein (WRN) is a RecQ-type DNA helicase, which seems to participate in DNA replication, double-strand break (DSB) repair, and telomere maintenance; however, its exact function remains elusive. Using Xe...

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Detalles Bibliográficos
Autores principales:	Yan, Hong, McCane, Jill, Toczylowski, Thomas, Chen, Chinyi
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171202/ https://www.ncbi.nlm.nih.gov/pubmed/16247024 http://dx.doi.org/10.1083/jcb.200502077

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