Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I

Mammalian MutL homologues function in DNA mismatch repair (MMR) after replication errors and in meiotic recombination. Both functions are initiated by a heterodimer of MutS homologues specific to either MMR (MSH2–MSH3 or MSH2–MSH6) or crossing over (MSH4–MSH5). Mutations of three of the four MutL ho...

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Detalles Bibliográficos
Autores principales: Kolas, Nadine K., Svetlanov, Anton, Lenzi, Michelle L., Macaluso, Frank P., Lipkin, Steven M., Liskay, R. Michael, Greally, John, Edelmann, Winfried, Cohen, Paula E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171243/
https://www.ncbi.nlm.nih.gov/pubmed/16260499
http://dx.doi.org/10.1083/jcb.200506170

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