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Desmoplakin assembly dynamics in four dimensions: multiple phases differentially regulated by intermediate filaments and actin
The intermediate filament (IF)–binding protein desmoplakin (DP) is essential for desmosome function and tissue integrity, but its role in junction assembly is poorly understood. Using time-lapse imaging, we show that cell–cell contact triggers three temporally overlapping phases of DP-GFP dynamics:...
Autores principales: | Godsel, Lisa M., Hsieh, Sherry N., Amargo, Evangeline V., Bass, Amanda E., Pascoe-McGillicuddy, Lauren T., Huen, Arthur C., Thorne, Meghan E., Gaudry, Claire A., Park, Jung K., Myung, Kyunghee, Goldman, Robert D., Chew, Teng-Leong, Green, Kathleen J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171300/ https://www.ncbi.nlm.nih.gov/pubmed/16365169 http://dx.doi.org/10.1083/jcb.200510038 |
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