Keratin 8 overexpression promotes mouse Mallory body formation

Keratins 8 and 18 (K8/18) are major constituents of Mallory bodies (MBs), which are hepatocyte cytoplasmic inclusions seen in several liver diseases. K18-null but not K8-null or heterozygous mice form MBs, which indicates that K8 is important for MB formation. Early stages in MB genesis include K8/1...

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Detalles Bibliográficos
Autores principales: Nakamichi, Ikuo, Toivola, Diana M., Strnad, Pavel, Michie, Sara A., Oshima, Robert G., Baribault, Hélène, Omary, M. Bishr
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171301/
https://www.ncbi.nlm.nih.gov/pubmed/16365160
http://dx.doi.org/10.1083/jcb.200507093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171301/
https://www.ncbi.nlm.nih.gov/pubmed/16365160
http://dx.doi.org/10.1083/jcb.200507093

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