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Support for the immortal strand hypothesis: neural stem cells partition DNA asymmetrically in vitro

The immortal strand hypothesis proposes that asymmetrically dividing stem cells (SCs) selectively segregate chromosomes that bear the oldest DNA templates. We investigated cosegregation in neural stem cells (NSCs). After exposure to the thymidine analogue 5-bromo-2-deoxyuridine (BrdU), which labels...

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Detalles Bibliográficos
Autores principales:	Karpowicz, Phillip, Morshead, Cindi, Kam, Angela, Jervis, Eric, Ramunas, John, Cheng, Vincent, van der Kooy, Derek
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171352/ https://www.ncbi.nlm.nih.gov/pubmed/16115957 http://dx.doi.org/10.1083/jcb.200502073

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