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FcɛRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane
The aggregation of high affinity IgE receptors (Fcɛ receptor I [FcɛRI]) on mast cells is potent stimulus for the release of inflammatory and allergic mediators from cytoplasmic granules. However, the molecular mechanism of degranulation has not yet been established. It is still unclear how FcɛRI-med...
Autores principales: | Nishida, Keigo, Yamasaki, Satoru, Ito, Yukitaka, Kabu, Koki, Hattori, Kotaro, Tezuka, Tohru, Nishizumi, Hirofumi, Kitamura, Daisuke, Goitsuka, Ryo, Geha, Raif S., Yamamoto, Tadashi, Yagi, Takeshi, Hirano, Toshio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171390/ https://www.ncbi.nlm.nih.gov/pubmed/15998803 http://dx.doi.org/10.1083/jcb.200501111 |
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