Cargando…

Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors

Internalization of activated receptors regulates signaling, and endocytic adaptor proteins are well-characterized in clathrin-mediated uptake. One of these adaptor proteins, huntingtin interacting protein 1 (HIP1), induces cellular transformation and is overexpressed in some prostate cancers. We hav...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mills, Ian G., Gaughan, Luke, Robson, Craig, Ross, Theodora, McCracken, Stuart, Kelly, John, Neal, David E.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171420/ https://www.ncbi.nlm.nih.gov/pubmed/16027218 http://dx.doi.org/10.1083/jcb.200503106

Ejemplares similares

Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer
por: McClurg, Urszula L., et al.
Publicado: (2015)

A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities
por: Kounatidou, Evangelia, et al.
Publicado: (2019)

IKBKE activity enhances AR levels in advanced prostate cancer via modulation of the Hippo pathway
por: Bainbridge, Alex, et al.
Publicado: (2020)

Transcriptional Regulation of the Huntingtin Gene
por: Thomson, Sarah B., et al.
Publicado: (2018)

Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation
por: Gaughan, Luke, et al.
Publicado: (2005)

Correction to ‘Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation’
por: Gaughan, Luke, et al.
Publicado: (2021)

Regulation of the androgen receptor by SET9-mediated methylation
por: Gaughan, Luke, et al.
Publicado: (2011)

Regulation of the androgen receptor by SET9-mediated methylation
por: Gaughan, Luke, et al.
Publicado: (2013)

Wild-type but not mutant huntingtin modulates the transcriptional activity of liver X receptors
por: Futter, M, et al.
Publicado: (2009)

Huntingtin exon 1 deletion does not alter the subcellular distribution of huntingtin and gene transcription in mice
por: Zhao, Xianxian, et al.
Publicado: (2022)

Phosphorylation of Mutant Huntingtin at Serine 116 Modulates Neuronal Toxicity
por: Watkin, Erin E., et al.
Publicado: (2014)

Phosphorylation of huntingtin at residue T3 is decreased in Huntington’s disease and modulates mutant huntingtin protein conformation
por: Cariulo, Cristina, et al.
Publicado: (2017)

Mutant CAG repeats of Huntingtin transcript fold into hairpins, form nuclear foci and are targets for RNA interference
por: de Mezer, Mateusz, et al.
Publicado: (2011)

The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer
por: Adamson, Beth, et al.
Publicado: (2023)

Normal Aging Modulates the Neurotoxicity of Mutant Huntingtin
por: Diguet, Elsa, et al.
Publicado: (2009)

The Influence of Huntingtin Protein Size on Nuclear Localization and Cellular Toxicity
por: Hackam, Abigail S., et al.
Publicado: (1998)

Differential Effect of HDAC3 on Cytoplasmic and Nuclear Huntingtin Aggregates
por: Mano, Tatsuo, et al.
Publicado: (2014)

Huntingtin Interacting Protein 1: a Merkel Cell Carcinoma Marker That Interacts with c-Kit
por: Ames, Heather M., et al.
Publicado: (2011)

Real-time imaging of Huntingtin aggregates diverting target search and gene transcription
por: Li, Li, et al.
Publicado: (2016)

Focal distortion of the nuclear envelope by huntingtin aggregates revealed by lamin immunostaining
por: Chapple, J. Paul, et al.
Publicado: (2008)

Huntingtin and the Synapse
por: Barron, Jessica C., et al.
Publicado: (2021)

Identification of Binding Sites in Huntingtin for the Huntingtin Interacting Proteins HIP14 and HIP14L
por: Sanders, Shaun S., et al.
Publicado: (2014)

Huntingtin Interacting Proteins and Pathological Implications
por: Liu, Li, et al.
Publicado: (2023)

A Huntingtin Peptide Inhibits PolyQ-Huntingtin Associated Defects
por: Arribat, Yoan, et al.
Publicado: (2013)

The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin
por: Seefelder, Manuel, et al.
Publicado: (2020)

The COOH-terminal domain of huntingtin interacts with RhoGEF kalirin and modulates cell survival
por: McClory, Hollis, et al.
Publicado: (2018)

Linking Huntingtin to motility
por: Tuma, Rabiya S.
Publicado: (2006)

Huntingtin Lowering Strategies
por: Marxreiter, Franz, et al.
Publicado: (2020)

Huntingtin Interacting Proteins Are Genetic Modifiers of Neurodegeneration
por: Kaltenbach, Linda S, et al.
Publicado: (2007)

Frequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell‐type‐specific
por: Jansen, Anne H.P., et al.
Publicado: (2016)

Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties
por: Riguet, Nathan, et al.
Publicado: (2021)

Mutant huntingtin messenger RNA forms neuronal nuclear clusters in rodent and human brains
por: Ly, Socheata, et al.
Publicado: (2022)

Polyglutamine Induced Misfolding of Huntingtin Exon1 is Modulated by the Flanking Sequences
por: Lakhani, Vinal V., et al.
Publicado: (2010)

Aggregation-Prone Proteins Modulate Huntingtin Inclusion Body Formation in Yeast
por: Kantcheva, Ralitsa B., et al.
Publicado: (2014)

A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity
por: Yao, Yuwei, et al.
Publicado: (2015)

Modulation of Huntingtin Toxicity by BAG1 is Dependent on an Intact BAG Domain
por: Liman, Jan, et al.
Publicado: (2010)

Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington’s Disease
por: Tousley, Adelaide, et al.
Publicado: (2019)

PIN1 Modulates Huntingtin Levels and Aggregate Accumulation: An In vitro Model
por: Carnemolla, Alisia, et al.
Publicado: (2017)

Promoters Are Differentially Sensitive to N-Terminal Mutant Huntingtin-Mediated Transcriptional Repression
por: Hogel, Matthew, et al.
Publicado: (2012)

Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription
por: Gao, Rui, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_msegs6gnjk33vfhfofhfodea2u