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A novel mechanism of actin filament processive capping by formin: solution of the rotation paradox
The FH2 domains of formin family proteins act as processive cappers of actin filaments. Previously suggested stair-stepping mechanisms of processive capping imply that a formin cap rotates persistently in one direction with respect to the filament. This challenges the formin-mediated mechanism of in...
Autores principales: | Shemesh, Tom, Otomo, Takanori, Rosen, Michael K., Bershadsky, Alexander D., Kozlov, Michael M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171452/ https://www.ncbi.nlm.nih.gov/pubmed/16157699 http://dx.doi.org/10.1083/jcb.200504156 |
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