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Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation

Maternal embryonic leucine zipper kinase (MELK) was previously identified in a screen for genes enriched in neural progenitors. Here, we demonstrate expression of MELK by progenitors in developing and adult brain and that MELK serves as a marker for self-renewing multipotent neural progenitors (MNPs...

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Detalles Bibliográficos
Autores principales: Nakano, Ichiro, Paucar, Andres A., Bajpai, Ruchi, Dougherty, Joseph D., Zewail, Amani, Kelly, Theresa K., Kim, Kevin J., Ou, Jing, Groszer, Matthias, Imura, Tetsuya, Freije, William A., Nelson, Stanley F., Sofroniew, Michael V., Wu, Hong, Liu, Xin, Terskikh, Alexey V., Geschwind, Daniel H., Kornblum, Harley I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171475/
https://www.ncbi.nlm.nih.gov/pubmed/16061694
http://dx.doi.org/10.1083/jcb.200412115