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A glue for heterochromatin maintenance: stable SUV39H1 binding to heterochromatin is reinforced by the SET domain
Trimethylation of histone H3 lysine 9 and the subsequent binding of heterochromatin protein 1 (HP1) mediate the formation and maintenance of pericentromeric heterochromatin. Trimethylation of H3K9 is governed by the histone methyltransferase SUV39H1. Recent studies of HP1 dynamics revealed that HP1...
Autores principales: | Krouwels, Ilke M., Wiesmeijer, Karien, Abraham, Tsion E., Molenaar, Chris, Verwoerd, Nico P., Tanke, Hans J., Dirks, Roeland W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171490/ https://www.ncbi.nlm.nih.gov/pubmed/16103223 http://dx.doi.org/10.1083/jcb.200502154 |
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