An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

Generation and turnover of phosphoinositides (PIs) must be coordinated in a spatial- and temporal-restricted manner. The small GTPase Rab5 interacts with two PI 3-kinases, Vps34 and PI3Kβ, suggesting that it regulates the production of 3-PIs at various stages of the early endocytic pathway. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Hye-Won, Hayashi, Mitsuko, Christoforidis, Savvas, Lacas-Gervais, Sandra, Hoepfner, Sebastian, Wenk, Markus R., Modregger, Jan, Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Nystuen, Arne, Frankel, Wayne N., Solimena, Michele, De Camilli, Pietro, Zerial, Marino
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171494/
https://www.ncbi.nlm.nih.gov/pubmed/16103228
http://dx.doi.org/10.1083/jcb.200505128

Ejemplares similares

Ejemplares similares