Cargando…

Aurora A activates D-TACC–Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules

Centrosomes are the dominant sites of microtubule (MT) assembly during mitosis in animal cells, but it is unclear how this is achieved. Transforming acidic coiled coil (TACC) proteins stabilize MTs during mitosis by recruiting Minispindles (Msps)/XMAP215 proteins to centrosomes. TACC proteins can be...

Descripción completa

Detalles Bibliográficos
Autores principales: Barros, Teresa P., Kinoshita, Kazuhisa, Hyman, Anthony A., Raff, Jordan W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171528/
https://www.ncbi.nlm.nih.gov/pubmed/16186253
http://dx.doi.org/10.1083/jcb.200504097