Growth factor–induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells

The cell surface heparan sulfate proteoglycan (HSPG) glypican-1 is up-regulated by pancreatic and breast cancer cells, and its removal renders such cells insensitive to many growth factors. We sought to explain why the cell surface HSPG syndecan-1, which is also up-regulated by these cells and is a...

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Detalles Bibliográficos
Autores principales: Ding, Kan, Lopez-Burks, Martha, Sánchez-Duran, José Antonio, Korc, Murray, Lander, Arthur D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171561/
https://www.ncbi.nlm.nih.gov/pubmed/16286510
http://dx.doi.org/10.1083/jcb.200508010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171561/
https://www.ncbi.nlm.nih.gov/pubmed/16286510
http://dx.doi.org/10.1083/jcb.200508010

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