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Specific integrin α and β chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms

Integrins are adhesion receptors that are crucial to the functions of multicellular organisms. Integrin-mediated adhesion is a complex process that involves both affinity regulation and cytoskeletal coupling, but the molecular mechanisms behind this process have remained incompletely understood. In...

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Detalles Bibliográficos
Autores principales: Fagerholm, Susanna C., Hilden, Tiina J., Nurmi, Susanna M., Gahmberg, Carl G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171568/
https://www.ncbi.nlm.nih.gov/pubmed/16301335
http://dx.doi.org/10.1083/jcb.200504016