Cargando…
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis
Although Rho regulates cytokinesis, little was known about the functions in mitosis of Cdc42 and Rac. We recently suggested that Cdc42 works in metaphase by regulating bi-orient attachment of spindle microtubules to kinetochores. We now confirm the role of Cdc42 by RNA interference and identify the...
Autores principales: | Oceguera-Yanez, Fabian, Kimura, Kazuhiro, Yasuda, Shingo, Higashida, Chiharu, Kitamura, Toshio, Hiraoka, Yasushi, Haraguchi, Tokuko, Narumiya, Shuh |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171585/ https://www.ncbi.nlm.nih.gov/pubmed/15642749 http://dx.doi.org/10.1083/jcb.200408085 |
Ejemplares similares
-
APC(CDH1) Targets MgcRacGAP for Destruction in the Late M Phase
por: Nishimura, Koutarou, et al.
Publicado: (2013) -
Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis
por: Cannet, Aude, et al.
Publicado: (2014) -
Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors
por: Kawashima, Toshiyuki, et al.
Publicado: (2006) -
Correction: APC(CDH1) Targets MgcRacGAP for Destruction in the Late M Phase
Publicado: (2014) -
Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP
por: van Adrichem, Arjan J., et al.
Publicado: (2015)