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The offloading model for dynein function: differential function of motor subunits

During mitosis in budding yeast, dynein moves the mitotic spindle into the mother-bud neck. We have proposed an offloading model to explain how dynein works. Dynein is targeted to the dynamic plus end of a cytoplasmic microtubule, offloads to the cortex, becomes anchored and activated, and then pull...

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Detalles Bibliográficos
Autores principales: Lee, Wei-Lih, Kaiser, Michelle A., Cooper, John A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171595/
https://www.ncbi.nlm.nih.gov/pubmed/15642746
http://dx.doi.org/10.1083/jcb.200407036

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