Cilia and the cell cycle?

A recent convergence of data indicating a relationship between cilia and proliferative diseases, such as polycystic kidney disease, has revived the long-standing enigma of the reciprocal regulatory relationship between cilia and the cell cycle. Multiple signaling pathways are localized to cilia in m...

Descripción completa

Detalles Bibliográficos
Autores principales: Quarmby, Lynne M., Parker, Jeremy D.K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171619/
https://www.ncbi.nlm.nih.gov/pubmed/15928206
http://dx.doi.org/10.1083/jcb.200503053
_version_ 1782144954344144896
author Quarmby, Lynne M.
Parker, Jeremy D.K.
author_facet Quarmby, Lynne M.
Parker, Jeremy D.K.
author_sort Quarmby, Lynne M.
collection PubMed
description A recent convergence of data indicating a relationship between cilia and proliferative diseases, such as polycystic kidney disease, has revived the long-standing enigma of the reciprocal regulatory relationship between cilia and the cell cycle. Multiple signaling pathways are localized to cilia in mammalian cells, and some proteins have been shown to act both in the cilium and in cell cycle regulation. Work from the unicellular alga Chlamydomonas is providing novel insights as to how cilia and the cell cycle are coordinately regulated.
format Text
id pubmed-2171619
institution National Center for Biotechnology Information
language English
publishDate 2005
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21716192008-03-05 Cilia and the cell cycle? Quarmby, Lynne M. Parker, Jeremy D.K. J Cell Biol Reviews A recent convergence of data indicating a relationship between cilia and proliferative diseases, such as polycystic kidney disease, has revived the long-standing enigma of the reciprocal regulatory relationship between cilia and the cell cycle. Multiple signaling pathways are localized to cilia in mammalian cells, and some proteins have been shown to act both in the cilium and in cell cycle regulation. Work from the unicellular alga Chlamydomonas is providing novel insights as to how cilia and the cell cycle are coordinately regulated. The Rockefeller University Press 2005-06-06 /pmc/articles/PMC2171619/ /pubmed/15928206 http://dx.doi.org/10.1083/jcb.200503053 Text en Copyright © 2005, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Reviews
Quarmby, Lynne M.
Parker, Jeremy D.K.
Cilia and the cell cycle?
title Cilia and the cell cycle?
title_full Cilia and the cell cycle?
title_fullStr Cilia and the cell cycle?
title_full_unstemmed Cilia and the cell cycle?
title_short Cilia and the cell cycle?
title_sort cilia and the cell cycle?
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171619/
https://www.ncbi.nlm.nih.gov/pubmed/15928206
http://dx.doi.org/10.1083/jcb.200503053
work_keys_str_mv AT quarmbylynnem ciliaandthecellcycle
AT parkerjeremydk ciliaandthecellcycle

Ejemplares similares