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Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion
It is well known that the products of chromosome replication are paired to ensure that the sisters segregate away from each other during mitosis. A key issue is how cells pair sister chromatids but preclude the catastrophic pairing of nonsister chromatids. The identification of both replication fact...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171654/ https://www.ncbi.nlm.nih.gov/pubmed/15955849 http://dx.doi.org/10.1083/jcb.200503129 |
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author | Skibbens, Robert V. |
author_facet | Skibbens, Robert V. |
author_sort | Skibbens, Robert V. |
collection | PubMed |
description | It is well known that the products of chromosome replication are paired to ensure that the sisters segregate away from each other during mitosis. A key issue is how cells pair sister chromatids but preclude the catastrophic pairing of nonsister chromatids. The identification of both replication factor C and DNA helicases as critical for sister chromatid pairing has brought new insights into this fundamental process. |
format | Text |
id | pubmed-2171654 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21716542008-03-05 Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion Skibbens, Robert V. J Cell Biol Reviews It is well known that the products of chromosome replication are paired to ensure that the sisters segregate away from each other during mitosis. A key issue is how cells pair sister chromatids but preclude the catastrophic pairing of nonsister chromatids. The identification of both replication factor C and DNA helicases as critical for sister chromatid pairing has brought new insights into this fundamental process. The Rockefeller University Press 2005-06-20 /pmc/articles/PMC2171654/ /pubmed/15955849 http://dx.doi.org/10.1083/jcb.200503129 Text en Copyright © 2005, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Reviews Skibbens, Robert V. Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion |
title | Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion |
title_full | Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion |
title_fullStr | Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion |
title_full_unstemmed | Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion |
title_short | Unzipped and loaded: the role of DNA helicases and RFC clamp-loading complexes in sister chromatid cohesion |
title_sort | unzipped and loaded: the role of dna helicases and rfc clamp-loading complexes in sister chromatid cohesion |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171654/ https://www.ncbi.nlm.nih.gov/pubmed/15955849 http://dx.doi.org/10.1083/jcb.200503129 |
work_keys_str_mv | AT skibbensrobertv unzippedandloadedtheroleofdnahelicasesandrfcclamploadingcomplexesinsisterchromatidcohesion |