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Inducible ablation of mouse Langerhans cells diminishes but fails to abrogate contact hypersensitivity

Langerhans cells (LC) form a unique subset of dendritic cells (DC) in the epidermis but so far their in vivo functions in skin immunity and tolerance could not be determined, in particular in relation to dermal DC (dDC). Here, we exploit a novel diphtheria toxin (DT) receptor (DTR)/DT-based system t...

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Detalles Bibliográficos
Autores principales: Bennett, Clare L., van Rijn, Erwin, Jung, Steffen, Inaba, Kayo, Steinman, Ralph M., Kapsenberg, Martien L., Clausen, Björn E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171694/
https://www.ncbi.nlm.nih.gov/pubmed/15897263
http://dx.doi.org/10.1083/jcb.200501071