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Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ

I*nterferon-γ (IFN-γ) is believed to contribute to immune-mediated demyelinating disorders by targeting the myelin-producing oligodendrocyte, a cell known to be highly sensitive to the disruption of protein synthesis and to the perturbation of the secretory pathway. We found that apoptosis induced b...

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Detalles Bibliográficos
Autores principales: Lin, Wensheng, Harding, Heather P., Ron, David, Popko, Brian
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171696/
https://www.ncbi.nlm.nih.gov/pubmed/15911877
http://dx.doi.org/10.1083/jcb.200502086