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Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ
I*nterferon-γ (IFN-γ) is believed to contribute to immune-mediated demyelinating disorders by targeting the myelin-producing oligodendrocyte, a cell known to be highly sensitive to the disruption of protein synthesis and to the perturbation of the secretory pathway. We found that apoptosis induced b...
Autores principales: | Lin, Wensheng, Harding, Heather P., Ron, David, Popko, Brian |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171696/ https://www.ncbi.nlm.nih.gov/pubmed/15911877 http://dx.doi.org/10.1083/jcb.200502086 |
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