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X chromosome choice occurs independently of asynchronous replication timing
In mammals, dosage compensation is achieved by X chromosome inactivation in female cells. Xist is required and sufficient for X inactivation, and Xist gene deletions result in completely skewed X inactivation. In this work, we analyzed skewing of X inactivation in mice with an Xist deletion encompas...
Autores principales: | Gribnau, Joost, Luikenhuis, Sandra, Hochedlinger, Konrad, Monkhorst, Kim, Jaenisch, Rudolf |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171734/ https://www.ncbi.nlm.nih.gov/pubmed/15668296 http://dx.doi.org/10.1083/jcb.200405117 |
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