Regulation of α5β1 integrin conformation and function by urokinase receptor binding

Urokinase-type plasminogen activator receptors (uPARs), up-regulated during tumor progression, associate with β1 integrins, localizing urokinase to sites of cell attachment. Binding of uPAR to the β-propeller of α3β1 empowers vitronectin adhesion by this integrin. How uPAR modifies other β1 integrin...

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Detalles Bibliográficos
Autores principales: Wei, Ying, Czekay, Ralf-Peter, Robillard, Liliane, Kugler, Matthias C., Zhang, Feng, Kim, Kevin K., Xiong, Jian-ping, Humphries, Martin J., Chapman, Harold A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171741/
https://www.ncbi.nlm.nih.gov/pubmed/15684035
http://dx.doi.org/10.1083/jcb.200404112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171741/
https://www.ncbi.nlm.nih.gov/pubmed/15684035
http://dx.doi.org/10.1083/jcb.200404112

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