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CDK4 regulation by TNFR1 and JNK is required for NF-κB–mediated epidermal growth control
Nuclear factor κB (NF-κB) mediates homeostatic growth inhibition in the epidermis, and a loss of NF-κB function promotes proliferation and oncogenesis. To identify mechanisms responsible for these effects, we impaired NF-κB action in the epidermis by three different genetic approaches, including con...
Autores principales: | Zhang, Jennifer Y., Tao, Shiying, Kimmel, Robin, Khavari, Paul A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171750/ https://www.ncbi.nlm.nih.gov/pubmed/15699216 http://dx.doi.org/10.1083/jcb.200411060 |
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