Botulinum neurotoxin C initiates two different programs for neurite degeneration and neuronal apoptosis

Clostridial neurotoxins are bacterial endopeptidases that cleave the major SNARE proteins in peripheral motorneurons. Here, we show that disruption of synaptic architecture by botulinum neurotoxin C1 (BoNT/C) in central nervous system neurons activates distinct neurodegenerative programs in the axo-...

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Detalles Bibliográficos
Autores principales: Berliocchi, Laura, Fava, Eugenio, Leist, Marcel, Horvat, Volker, Dinsdale, David, Read, David, Nicotera, Pierluigi
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171755/
https://www.ncbi.nlm.nih.gov/pubmed/15716378
http://dx.doi.org/10.1083/jcb.200406126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171755/
https://www.ncbi.nlm.nih.gov/pubmed/15716378
http://dx.doi.org/10.1083/jcb.200406126

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