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Temporal separation of replication and recombination requires the intra-S checkpoint
In response to DNA damage and replication pausing, eukaryotes activate checkpoint pathways that prevent genomic instability by coordinating cell cycle progression with DNA repair. The intra-S-phase checkpoint has been proposed to protect stalled replication forks from pathological rearrangements tha...
Autores principales: | Meister, Peter, Taddei, Angela, Vernis, Laurence, Poidevin, Mickaël, Gasser, Susan M., Baldacci, Giuseppe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171758/ https://www.ncbi.nlm.nih.gov/pubmed/15716375 http://dx.doi.org/10.1083/jcb.200410006 |
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