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ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles

Rho-associated kinase (ROCK) I mediates signaling from Rho to the actin cytoskeleton. To investigate the in vivo functions of ROCK-I, we generated ROCK-I–deficient mice. Loss of ROCK-I resulted in failure of eyelid closure and closure of the ventral body wall, which gave rise to the eyes open at bir...

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Detalles Bibliográficos
Autores principales:	Shimizu, Yoshihiko, Thumkeo, Dean, Keel, Jeongsin, Ishizaki, Toshimasa, Oshima, Hiroko, Oshima, Masanobu, Noda, Yoichi, Matsumura, Fumio, Taketo, Makoto M., Narumiya, Shuh
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171774/ https://www.ncbi.nlm.nih.gov/pubmed/15753128 http://dx.doi.org/10.1083/jcb.200411179

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