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Bcl-X(L) specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum

Bcl-2 family members Bak and Bax constitute a mitochondrial gateway for multiple death pathways. Both proteins are also present in the endoplasmic reticulum where they control apoptosis through the regulation of calcium levels. We show here that reticular Bak has the additional capacity of modulatin...

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Detalles Bibliográficos
Autores principales:	Klee, Martina, Pimentel-Muiños, Felipe X.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171806/ https://www.ncbi.nlm.nih.gov/pubmed/15728194 http://dx.doi.org/10.1083/jcb.200408169

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