Regulation of the interaction between PIPKIγ and talin by proline-directed protein kinases

The interaction of talin with phosphatidylinositol(4) phosphate 5 kinase type Iγ (PIPKIγ) regulates PI(4,5)P(2) synthesis at synapses and at focal adhesions. Here, we show that phosphorylation of serine 650 (S650) within the talin-binding sequence of human PIPKIγ blocks this interaction. At synapses...

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Detalles Bibliográficos
Autores principales: Lee, Sang Yoon, Voronov, Sergey, Letinic, Kresimir, Nairn, Angus C., Di Paolo, Gilbert, De Camilli, Pietro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171813/
https://www.ncbi.nlm.nih.gov/pubmed/15738269
http://dx.doi.org/10.1083/jcb.200409028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171813/
https://www.ncbi.nlm.nih.gov/pubmed/15738269
http://dx.doi.org/10.1083/jcb.200409028

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