N-myristoylation determines dual targeting of mammalian NADH-cytochrome b(5) reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning

Mammalian NADH-cytochrome b(5) reductase (b5R) is an N-myristoylated protein that is dually targeted to ER and mitochondrial outer membranes. The N-linked myristate is not required for anchorage to membranes because a stretch of hydrophobic amino acids close to the NH(2) terminus guarantees a tight...

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Detalles Bibliográficos
Autores principales: Colombo, Sara, Longhi, Renato, Alcaro, Stefano, Ortuso, Francesco, Sprocati, Teresa, Flora, Adriano, Borgese, Nica
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171821/
https://www.ncbi.nlm.nih.gov/pubmed/15738266
http://dx.doi.org/10.1083/jcb.200407082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171821/
https://www.ncbi.nlm.nih.gov/pubmed/15738266
http://dx.doi.org/10.1083/jcb.200407082

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