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The subendothelial extracellular matrix modulates NF-κB activation by flow: a potential role in atherosclerosis

Atherosclerotic plaque forms in regions of the vasculature exposed to disturbed flow. NF-κB activation by fluid flow, leading to expression of target genes such as E-selectin, ICAM-1, and VCAM-1, may regulate early monocyte recruitment and fatty streak formation. Flow-induced NF-κB activation is dow...

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Detalles Bibliográficos
Autores principales:	Orr, A. Wayne, Sanders, John M., Bevard, Melissa, Coleman, Elizabeth, Sarembock, Ian J., Schwartz, Martin Alexander
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171897/ https://www.ncbi.nlm.nih.gov/pubmed/15809308 http://dx.doi.org/10.1083/jcb.200410073

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