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PI(4,5)P(2)-dependent microdomain assemblies capture microtubules to promote and control leading edge motility
The lipid second messenger PI(4,5)P(2) modulates actin dynamics, and its local accumulation at plasmalemmal microdomains (rafts) might mediate regulation of protrusive motility. However, how PI(4,5)P(2)-rich rafts regulate surface motility is not well understood. Here, we show that upon signals prom...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171909/ https://www.ncbi.nlm.nih.gov/pubmed/15809307 http://dx.doi.org/10.1083/jcb.200407058 |