Capacitative calcium entry: sensing the calcium stores

A long-standing mystery in the cell biology of calcium channel regulation is the nature of the signal linking intracellular calcium stores to plasma membrane capacitative calcium entry channels. An RNAi-based screen of selected Drosophila genes has revealed that a calcium-binding protein, stromal in...

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Detalles Bibliográficos
Autor principal: Putney, James W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171919/
https://www.ncbi.nlm.nih.gov/pubmed/15866892
http://dx.doi.org/10.1083/jcb.200503161
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author Putney, James W.
author_facet Putney, James W.
author_sort Putney, James W.
collection PubMed
description A long-standing mystery in the cell biology of calcium channel regulation is the nature of the signal linking intracellular calcium stores to plasma membrane capacitative calcium entry channels. An RNAi-based screen of selected Drosophila genes has revealed that a calcium-binding protein, stromal interaction molecule (STIM), plays an essential role in the activation of these channels and may be the long sought sensor of calcium store content.
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spelling pubmed-21719192008-03-05 Capacitative calcium entry: sensing the calcium stores Putney, James W. J Cell Biol Reviews A long-standing mystery in the cell biology of calcium channel regulation is the nature of the signal linking intracellular calcium stores to plasma membrane capacitative calcium entry channels. An RNAi-based screen of selected Drosophila genes has revealed that a calcium-binding protein, stromal interaction molecule (STIM), plays an essential role in the activation of these channels and may be the long sought sensor of calcium store content. The Rockefeller University Press 2005-05-09 /pmc/articles/PMC2171919/ /pubmed/15866892 http://dx.doi.org/10.1083/jcb.200503161 Text en Copyright © 2005, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Reviews
Putney, James W.
Capacitative calcium entry: sensing the calcium stores
title Capacitative calcium entry: sensing the calcium stores
title_full Capacitative calcium entry: sensing the calcium stores
title_fullStr Capacitative calcium entry: sensing the calcium stores
title_full_unstemmed Capacitative calcium entry: sensing the calcium stores
title_short Capacitative calcium entry: sensing the calcium stores
title_sort capacitative calcium entry: sensing the calcium stores
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171919/
https://www.ncbi.nlm.nih.gov/pubmed/15866892
http://dx.doi.org/10.1083/jcb.200503161
work_keys_str_mv AT putneyjamesw capacitativecalciumentrysensingthecalciumstores

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