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Integrins control motile strategy through a Rho–cofilin pathway
During wound healing, angiogenesis, and tumor invasion, cells often change their expression profiles of fibronectin-binding integrins. Here, we show that β1 integrins promote random migration, whereas β3 integrins promote persistent migration in the same epithelial cell background. Adhesion to fibro...
Autores principales: | Danen, Erik H.J., van Rheenen, Jacco, Franken, Willeke, Huveneers, Stephan, Sonneveld, Petra, Jalink, Kees, Sonnenberg, Arnoud |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2171933/ https://www.ncbi.nlm.nih.gov/pubmed/15866889 http://dx.doi.org/10.1083/jcb.200412081 |
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